Actress Christina Applegate used the latest episode of her “MeSsy” podcast to share a significant health update with listeners. After years of living with a multiple sclerosis (MS) diagnosis, a recent medical evaluation revealed that she does not, in fact, have the autoimmune disorder.
From diagnosis to clarification
Applegate first went public with an MS diagnosis in 2021, joining a growing list of public figures who have spoken about the disease. In a recent episode recorded last week, she explained that a neurologist informed her that her symptoms do not meet the criteria for MS. The doctor’s assessment aligns with research indicating that roughly one‑in‑five patients initially diagnosed with MS are later found not to have the condition.
Continuing advocacy
Despite the misdiagnosis, Applegate emphasized that she will remain a “warrior” for the MS community. “You guys are my people,” she said, addressing listeners. “I’m still your warrior and I’ll keep speaking out on your behalf forever and ever.” She added that the support she has received from fans and fellow advocates has been overwhelming and that she intends to keep raising awareness about both MS and the challenges of misdiagnosis.
New health hurdles
While relieved to learn she does not have MS, Applegate described ongoing mobility issues that have emerged. She recounted a recent morning in which it took her ten minutes to sit up, get out of bed, and stand, after which she struggled to walk to the bathroom. A walker now sits beside her bed to assist with movement. “I don’t know what’s going on,” she said, acknowledging the uncertainty surrounding her current symptoms.
Medical perspective
Dr. Marwa Kaisey, a board‑certified neurologist and associate professor at Cedars‑Sinai Medical Center, has previously discussed the difficulty of diagnosing MS on the “MeSsy” podcast. She explained that there is no single definitive test for the disease; diagnosis relies on a combination of clinical evaluation, imaging studies, and laboratory results, all of which can evolve over time. Misdiagnosis can occur when symptoms overlap with other neurological conditions or when diagnostic criteria are applied incorrectly.
Looking ahead
Applegate said she will continue co‑hosting the “MeSsy” podcast with actress Jamie Lynn Sigler, who also lives with MS. She expressed gratitude for the outpouring of love and urged listeners to stay hopeful while seeking appropriate medical care. “I can’t get my hopes up,” she admitted, but she remains committed to supporting the community that has supported her.
Community response
Fans and fellow advocates have flooded social media with messages of encouragement, praising Applegate for her transparency and dedication. Many highlighted the importance of accurate diagnosis and the need for continued research into both MS and conditions that mimic its symptoms.
ABC News contributor Mary Kekatos provided additional reporting for this story.
Original reporting: Brookhaven News – ABC7 New York — read the source article.
