A recent study found that the time of day when cancer treatment is administered can significantly impact its effectiveness. Patients who received their first rounds of immunotherapy treatments in the morning had, on average, about five more months before their cancers grew and spread, compared to those who received their treatments later in the day.

Understanding the Circadian Rhythm

Researchers have long studied the body’s internal clock, or circadian rhythm, which governs various biological functions, including the release of hormones, hunger, and sleep patterns. The immune system is also sensitive to timing, with evidence suggesting that the timing of treatments can influence their effectiveness.

The study, which involved 210 patients with non-small-cell lung cancer, found that those who received their treatments before 3 p.m. had better outcomes than those who received their treatments later in the day. The patients in the early treatment group survived nearly a year longer, on average, and had a lower risk of cancer progression.

While the findings are promising, experts are approaching with caution, citing the need for further research to understand the underlying mechanisms. The study’s authors are calling for a coordinated effort to investigate the impact of timing on cancer treatment, with at least one confirmatory study already underway.

The research has significant implications for the treatment of cancer, highlighting the importance of considering the timing of treatments in addition to their type and dosage. As the study’s authors note, the findings could lead to more effective treatment strategies and improved patient outcomes.

Original reporting: KRDO (Colorado Springs metro) — read the source article.