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Nov 13, 2026
HyperLocal Loop
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Mayo Clinic Names Dr. Matthew Callstrom as New President and CEO

Rochester, MN – The Mayo Clinic Board of Trustees announced today that Dr. Matthew R. Callstrom will become the organization’s next president and chief executive officer, succeeding Dr. Gianrico Farrugia at the end of the year. The transition is intended to be seamless, with Dr. Farrugia remaining in his role through December to guide the hand‑off.

Deep Roots in Mayo’s Mission

Dr. Callstrom has spent 24 years at Mayo Clinic, most recently serving as medical director for Mayo Clinic Strategy and the AI program. Earlier, he was interim chief strategy officer and chair of the Department of Radiology in Rochester. In those roles, he helped shape the institution’s strategic direction and oversaw the responsible integration of artificial intelligence into clinical practice, aiming to accelerate discovery, detect disease earlier, and give clinicians new tools for complex cases.

Commitment to Innovation and Patient Care

“I am deeply honored to have the opportunity to lead Mayo Clinic in this moment, serving alongside colleagues whose expertise, curiosity and commitment to our patients inspire me every day,” Dr. Callstrom said in the release. “Mayo Clinic has always been at its best when we bring the full power of our clinical expertise, science and innovation to the needs of the patient. Now, we have an opportunity to build on that foundation – accelerating the translation of discovery and emerging technologies into better care and extending Mayo Clinic’s impact to more patients, wherever they are.”

Recognized Expertise in Cancer Treatment

Dr. Callstrom is internationally recognized for advancing image‑guided cancer treatment, including the development of technologies that more precisely identify and treat tumors. He has been honored as a Mayo Clinic Distinguished Clinician and previously served as president of the Society of Interventional Oncology.

Educational Background

A Minnesota native, Dr. Callstrom earned degrees in chemical engineering and chemistry from the University of Minnesota, completed a postdoctoral fellowship at Harvard University, and received his medical degree from the Mayo Clinic Alix School of Medicine.

Legacy of Growth Under Dr. Farrugia

Dr. Farrugia, who has led Mayo Clinic since 2019, is credited with launching the “Bold. Forward. Unbound.” initiative that drove more than $5 billion in expansion projects throughout Rochester. He praised Dr. Callstrom’s deep institutional knowledge and vision, stating, “I have great confidence in him and in Mayo Clinic’s future.”

The leadership change underscores Mayo Clinic’s ongoing commitment to combining world‑class patient care with cutting‑edge research and technology, a blend that has long defined the Rochester institution’s reputation both nationally and globally.


Original reporting: News Talk 1340 KROC-AM – News and Talk – Rochester News Radio — read the source article.

OBBM Network Editorial Staff

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